Histamine complex dating
Docking of various second-generation H, both of which form part of the anion-binding region.
If you have histamine intolerance, some potential therapeutic options include: Histamine intolerance comes about as a result of too little histamine-degrading enzymes in your gut (DAO). This causes numerous symptoms that resemble an allergic reaction It can come from gut damage, alcohol, drugs/supplements or a microbial imbalance.
If a lack of DAO is the sole cause of your histamine issues, then all you need to do is take the enzyme.
The study, "Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex," which will be published online October 24 ahead of issue in Mast cells are a type of white blood cell localized in most tissues of the body that fight off parasitic infections by releasing histamine and other inflammatory factors contained in secretory granules.
But allergens can also trigger granule release, and, if this happens simultaneously in mast cells throughout the body, it can provoke a life-threatening anaphylactic response that leads to facial swelling, difficulty breathing, a drop in blood pressure, and fainting.
Two teams of researchers led by Ulrich Blank (CNRS) of the Center of Research on Inflammation (CNRS) and Gaël Ménasché (INSERM) of the Imagine Institute in Paris, France, investigated the role of kinesin-1, a motor protein that transports various cargoes along microtubules.